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35) Zhouyao, H., Zimmer, A.M., Fehsenfeld, S., Liebenstein, T., Richter, D.O., Begemann, G., Eck, P., Perry, S.F., Weihrauch, D. (2022) Characterization of two novel ammonia transporters, Hiat1a and Hiat1b, in the teleost model system Danio rerio. J Exp Biol 225, jeb244279

†Shortlisted for Outstanding Paper Prize

34) Zimmer, A.M., Perry, S.F. (2022) Physiology and aquaculture: A review of ion and acid-base regulation by the gills of fishes. Fish Fish 23, 874-898

33) Zimmer, A.M., Goss, G.G., Glover, C.N. (2021) Chemical niches and ionoregulatory traits: applying ionoregulatory physiology to the conservation management of freshwater fishes. Conserv Physiol 9: coab066

32) Giacomin, M., Glover, C.N., Goss, G.G., Zimmer, A.M. (2021) The skin of adult rainbow trout is not a significant site of ammonia clearance from the blood. J Fish Biol 99: 1529-1534

31) Zimmer, A.M., Goss, G.G., Glover, C.N. (2021) Reductionist approaches to the study of ionoregulation in fishes. Comp Biochem Physiol B 255: 110597

30) Zimmer, A.M.*, Mandic, M.*, Yew, H.M., Kunert, E., Pan, Y.K., Ha, J., Kwong, R.W.M., Gilmour, K.M., Perry, S.F. (2021) Use of carbonic anhydrase Ca17a knockout to investigate mechanisms of ion uptake in zebrafish (Danio rerio). Am J Physiol Regul Integr Comp Physiol 320: R55-R68

*Both authors contributed equally

29) Hare, A.J., Zimmer, A.M., LePabic, R., Morgan, A.L., Gilmour, K.M. (2021) Early-life stress influences ion balance in developing zebrafish (Danio rerio). J Comp Physiol B 191: 69-84

28) Parker, J.J., Zimmer, A.M., Perry, S.F. (2020) Respirometry and cutaneous oxygen flux measurements reveal a negligible cost of ion regulation in larval zebrafish (Danio rerio). J Exp Biol 223: jeb226753

27) Zimmer, A.M., Perry, S.F. (2020) The Rhesus glycoprotein Rhcgb is expendable for ammonia excretion and Na+ uptake in zebrafish (Danio rerio). Comp Biochem Physiol A 247: 110722

26) Yew, H.M., Zimmer, A.M., Perry, S.F. (2020) Assessing intracellular pH regulation in H+-ATPase-rich ionocytes in zebrafish larvae using in vivo ratiometric imaging. J Exp Biol 223: jeb212928

25) Zimmer, A.M., Shir-Mohammadi, K., Kwong, R.M.W., Perry, S.F. (2020) Reassessing the contribution of the Na+/H+ exchanger Nhe3b to Na+ uptake in zebrafish (Danio rerio) using CRISPR/Cas9 gene editing. J Exp Biol 223: jeb215111

24) Zimmer, A.M.*, Mandic, M.*, Rourke, K.M., Perry, S.F. Breathing with fins: do the pectoral fins of larval fishes play a respiratory role? (2020) Am J Physiol Regul Integr Comp Physiol 318: R89-R97

*Authors contributed equally to study

†Featured in an “Outside JEB” article – Borowiec (2020) J Exp Biol 223: jeb211482

23) Zimmer, A.M., Do, J., Szederkenyi, K., Chen, A., Morgan, A.L.R., Jensen, G., Pan, Y.K., Gilmour, K.M., Perry, S.F. (2019) Use of gene knockout to examine serotonergic control of ion uptake in zebrafish reveals the importance of controlling for genetic background: A cautionary tale. Comp Biochem Physiol A 238: 110558

22) Pan, Y.K., Mandic, M.M., Zimmer, A.M., Perry, S.F. (2019) Evaluating the physiological significance of hypoxic hyperventilation in larval zebrafish (Danio rerio). J Exp Biol 222: jeb204800

21) Zimmer, A.M.*, Pan, Y.K.*, Chandrapalan, T., Kwong, R.W.M., Perry, S.F. (2019) Loss-of-function approaches in comparative physiology: is there a future for knockdown experiments in the era of genome editing?. J Exp Biol 222: jeb175737

*Authors contributed equally to study


20) Hughes, M., Zimmer, A.M., Perry, S.F. (2019) Role of internal convection in respiratory gas transfer and aerobic metabolism in larval zebrafish (Danio rerio). Am J Physiol Regul Integr Comp Physiol 316: R255–R264

19) Zimmer, A.M., Brix, K.V., Wood, C.M. (2019) Mechanisms of Ca2+ uptake in freshwater and seawater-acclimated killifish, Fundulus heteroclitus, and their response to acute salinity transfer. J Comp Physiol B 189:47–60

18) Zimmer, A.M.*, Dymowska, A.K.*, Kumai, Y., Goss, G.G., Perry, S.F., Kwong, R.W.M. (2018) Assessing the role of the acid-sensing ion channel ASIC4b in Na+ uptake by larval zebrafish. Comp Biochem Physiol A 226: 1-10

*Authors contributed equally to study


17) Zimmer, A.M., Wright, P.A., Wood, C.M. (2017) Review: Ammonia and urea handling by early life stages of fishes. J Exp Biol 220, 3843-3855

16) Zimmer, A.M., Wilson, J.M., Wright, P.A., Hiroi, J., Wood, C.M. (2017) Different mechanisms of Na+ uptake and ammonia excretion by the gill and yolk sac epithelium of early life stage rainbow trout. J Exp Biol 220: 775-786


15) Zimmer, A.M., Basso Jorge, M., Wood, C.M., Martins, C.M.G., Bianchini, A. (2017) The effects of acute copper and ammonia challenges on ammonia and urea excretion by the blue crab Callinectes sapidus. Arch Environ Contam Toxicol 72: 461-470    


14) Zimmer, A.M., Wood, C.M. (2017) Acute exposure to high environmental ammonia (HEA) triggers the emersion response in the green shore crab. Comp Biochem Physiol A 204: 65-75

13) Clifford, A.C., Zimmer, A.M., Wood, C.M., Goss, G.G. (2016) It’s all in the gills: evaluation of O2 uptake in the Pacific hagfish refutes a major respiratory role for the skin. J Exp Biol 219: 2814-2818


12) Zimmer, A.M., Wood, C.M. (2016) Physiological and molecular ontogeny of branchial and extra-branchial urea excretion in posthatch rainbow trout (Oncorhynchus mykiss). Am J Physiol Regul Integr Comp Physiol 310: R305-R312

†Featured as “Editor’s Choice”


11) Zimmer, A.M., Wood, C.M. (2015) Ammonia first? The transition from cutaneous to branchial ammonia excretion in developing rainbow trout is not altered by exposure to chronically high NaCl. J Exp Biol 218:1467-1470

10) Rubino, J.G., Zimmer, A.M., Wood, C.M. (2015) Intestinal ammonia transport in freshwater and seawater acclimated rainbow trout (Oncorhynchus mykiss): Evidence for a Na+ coupled uptake mechanism. Comp Biochem Physiol A 183: 45-56

9) Lim, M. Y.-T., Zimmer, A.M., Wood, C.M. (2015) Acute exposure to waterborne copper inhibits both the excretion and uptake of ammonia in freshwater rainbow trout (Oncorhynchus mykiss). Comp Biochem Physiol C 168: 48-54

8) Zimmer, A.M., Wright, P.A., Wood, C.M. (2014) What is the primary function of the early teleost gill? Evidence for Na+/NH4+ exchange in developing rainbow trout (Oncorhynchus mykiss). Proc Royal Soc B 281, 20141422


7) Zimmer, A.M., Wood, C.M. (2014) Exposure to acute severe hypoxia leads to increased urea loss and disruptions in acid-base and ionoregulatory balance in dogfish sharks (Squalus acanthias). Physiol Biochem Zool 87: 623-639

6) Zimmer, A.M., Brauner, C.J., Wood, C.M. (2014) Exposure to waterborne Cu inhibits cutaneous Na+ uptake in post-hatch larval rainbow trout (Oncorhynchus mykiss). Aquat Tox 150: 151-158

5) Zimmer, A.M., Brauner, C.J., Wood, C.M. (2014) Ammonia transport across the skin of adult rainbow trout (Oncorhynchus mykiss) exposed to high environmental ammonia (HEA). J Comp Physiol B 184: 77-90

4) Rubino J.G., Zimmer, A.M., Wood, C.M. (2014) An in vitro analysis of intestinal ammonia handling in fasted and fed freshwater rainbow trout (Oncorhynchus mykiss). J Comp Physiol B 184: 91-105


3) Zimmer, A.M., Barcarolli, I.F., Wood, C.M., Bianchini, A. (2012) Waterborne copper exposure inhibits ammonia excretion and branchial carbonic anhydrase activity in euryhaline guppies acclimated to both fresh water and sea water. Aquat Tox 122-123: 172-180

2) Smith, A.A., Zimmer, A.M., Wood, C.M. (2012) Branchial and extra-branchial ammonia excretion in goldfish (Carassius auratus) following thermally induced gill remodeling. Comp Biochem Physiol A 162: 185-192                         

1) Zimmer, A.M., Nawata C.M., Wood, C.M. (2010) Physiological and molecular analysis of the interactive effects of feeding and high ammonia on branchial ammonia excretion and Na+ uptake in freshwater rainbow trout. J Comp Physiol B 180: 1191–1204

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